Research Associate, Protein Biochemistry

Job Length: 6+ Months

Job Summary: Individual will actively contribute to the development of novel biological molecules for multiple disease indications.

Job Responsibilities:

• Primary responsibilities for protein expression, purification, and characterization.
• Development and execution of quantitative PK/PD/ADA assays to support preclinical in vivo studies.
• Development and execution of analytical and biochemical assays to characterize biological molecules.
• Participate in advancing the company pipeline and capabilities in biologics.
• Maintain Cell culture and reagents inventory.

 

Job Requirements:

• Experience with Mammalian cell culture-Expi-HEK293 & Expi-CHO
• Experience with Biologic / Protein expression and purification
• Experience with AKTA FPLC purification systems required
• Experience in standard ELISA/MSD required
• Protein characterization: biophysical techniques to include SDS-PAGE, size exclusion chromatography (SEC), Agilent HPLC, and Biacore/Octet; Mass spectrometry
• Additional experience in standard molecular and cell biology techniques (western, mammalian cell culture); experience in protein design and engineering
• Experimental design, analysis, and interpretation of data.
• Ability to identify and troubleshoot experimental problems, seeking advice or consulting literature if necessary.
• BS/MS with 3+ year experience, preferably in a biotechnology or pharmaceutical setting, degree in a relevant scientific discipline (biochemistry, biophysics, chemistry, and biology)